FB2026_02 , released June 18, 2026
Gene Group: RAN GUANINE NUCLEOTIDE EXCHANGE FACTORS
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General Information
Name
RAN GUANINE NUCLEOTIDE EXCHANGE FACTORS
Species
D. melanogaster
Symbol
RANGEF
FlyBase ID
FBgg0000338
Date last reviewed
2015-10-16
Number of members
1
Description
Description
Ran Guanine Nucleotide Exchange Factor (RanGEF) promotes the exchange of Ran-bound GDP for GTP on nucleoplasmic side of the nuclear pore as part of the nucleocytoplasmic transport shuttling cycle of Ran. (Adapted from FBrf0174533).
Notes on Group
Source Material
The RAN GUANINE NUCLEOTIDE EXCHANGE FACTORS Gene Group has been compiled using the following publication(s): Shi and Skeath, 2004 .
Key Gene Ontology (GO) terms
Molecular Function
guanyl-nucleotide exchange factor activity
Biological Process
NLS-bearing protein import into nucleus
mRNA export from nucleus
protein export from nucleus
Cellular Component
nucleus
Related Gene Groups
Parent group(s)
RAS SUPERFAMILY GUANINE NUCLEOTIDE EXCHANGE FACTORS
Other related group(s)
RAN GTPASE ACTIVATING PROTEINS
RAN GTPASES
Members (1)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
RANGEF
RAN GUANINE NUCLEOTIDE EXCHANGE FACTORS
Ras-like nuclear GEF
Ran-GEF
Secondary FlyBase ID(s)
References (2)