The cyclin-dependent kinase (CDK)-activating kinase-Xeroderma pigmentosum D (CAK-XPD) complex is a four-subunit kinase module. CAK-XPD has a role in the regulation of the cell cycle progression in mitosis, where XPD negatively regulates the cell cycle function of the CAK activity. (Adapted from
FBrf0227236,
FBrf0211947,
FBrf0159708 and
PMID:21592869).