Gene Group: DYNEIN LIGHT INTERMEDIATE CHAINS

General Information

Name

DYNEIN LIGHT INTERMEDIATE CHAINS

Species

D. melanogaster

Symbol

DYN-LIC

FlyBase ID

FBgg0000383

Date last reviewed

2016-01-21

Number of members

Description

Dyneins are minus end-directed microtubule motor protein complexes. Dynein light intermediate chains (LIC) are subunits of dynein complexes. In cytoplasmic dynein complexes, dynein LIC binds as a dimer to dynein heavy chains and is involved in cargo attachment. (Adapted from PMID:19935668 and FBrf0206979).

Notes on Group

Although Dlic has a P-loop/G domain, it probably does not possess GTPase activity. Human cytoplasmic light intermediate chain 1 (DYNC1LI1) preferentially binds GDP (PMID:25272277).

Source Material

The DYNEIN LIGHT INTERMEDIATE CHAINS Gene Group has been compiled using the following publication(s): Mische et al., 2008 and Pfister et al., 2006 .

Key Gene Ontology (GO) terms

Molecular Function

dynein heavy chain binding

Biological Process

microtubule-based movement

Cellular Component

dynein complex

Related Gene Groups

Parent group(s)

DYNEIN SUBUNITS

Members (2)

For all members: