FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: SPERM-SPECIFIC DYNEIN INTERMEDIATE CHAINS
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General Information
Name
SPERM-SPECIFIC DYNEIN INTERMEDIATE CHAINS
Species
D. melanogaster
Symbol
SDIC
FlyBase ID
FBgg0000389
Date last reviewed
2017-01-16
Number of members
7
Description
Description
The sperm-specific dynein intermediate chains (Sdic) are encoded as a multigene family. Present only in Drosophila melanogaster, the Sdic cluster was recently evolutionary derived from the cytoplasmic dynein intermediate chain gene sw. The protein encoded by Sdic genes lacks the N-terminal region of sw, a region that contains a coiled-coil domain and a serine-rich domain which are essential for cytoplasmic dynein intermediate chain function. (Adapted from FBrf0195004).
Notes on Group

Whether all the Sdic genes are transcribed and translated into functional proteins is unclear and the cluster may encode additional Sdic genes (FBrf0195004, FBrf0217456).

FBrf0234399 provides a new analysis of the Sdic gene cluster. The authors report that gene number and arrangement differs between the Release 6 (FBrf0227324) and the Berlin assemblies (FBrf0228696) and that the latter model, which lacks CG46276, is a more accurate representation of this region.

Source Material
The SPERM-SPECIFIC DYNEIN INTERMEDIATE CHAINS Gene Group has been compiled using the following publication(s): Clifton et al., 2017, Karak et al., 2015, Yeh et al., 2012, Ponce and Hartl, 2006, and Nurminsky et al., 1998 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
DYNEIN INTERMEDIATE CHAINS
Members (7)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SDIC
SPERM-SPECIFIC DYNEIN INTERMEDIATE CHAINS
Secondary FlyBase ID(s)
References (6)