FB2026_03 , released September 17, 2026
Gene Group: WISKOTT-ALDRICH SYNDROME PROTEINS
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General Information
Name
WISKOTT-ALDRICH SYNDROME PROTEINS
Species
D. melanogaster
Symbol
WASP
FlyBase ID
FBgg0000493
Date last reviewed
2016-04-06
Number of members
4
Description
Description
The Wiskott-Aldrich Syndrome Proteins (WASP) are a family of nucleation-promoting factors. WASP proteins share a conserved Arp2/3-complex-activating C-terminal VCA/WCA (verprolin/WASP, cofilin, acidic) domain. WASP members participate in cytoskeleton organization, notably through the stimulation of the actin-nucleating activity of the Arp2/3 complex. (Adapted from FBrf0230860 and FBrf0217509).
Notes on Group
Source Material
The WISKOTT-ALDRICH SYNDROME PROTEINS Gene Group has been compiled using the following publication(s): Brinkmann et al., 2016, Verboon et al., 2015, and Rodriguez-Mesa et al., 2012 .
Key Gene Ontology (GO) terms
Molecular Function
cytoskeletal protein binding
Biological Process
actin cytoskeleton organization
Cellular Component
Related Gene Groups
Protein Complex group(s)
ACTIN-RELATED PROTEIN 2/3 COMPLEXES
WASP AND SCAR HOMOLOG COMPLEX
WAVE REGULATORY COMPLEX
Members (4)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
WASP
WISKOTT-ALDRICH SYNDROME PROTEINS
WAS family proteins
Secondary FlyBase ID(s)
References (4)