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General Information
Name
HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES
Species
D. melanogaster
Symbol
HSP40
FlyBase ID
FBgg0000504
Date last reviewed
2016-05-09
Number of members
43
Description
Description

The Heat Shock Protein 40 (Hsp40) family of co-chaperones are essential factors in the Hsp70 chaperone cycle. The Hsp40 family is diverse in size and structure, but a number of them are about 40kDa and have been identified as products of heat shock genes. Their defining feature is the DnaJ or J-domain corresponding to the N-terminal 70 amino acids of the Escherichia coli co-chaperone DnaJ. (Adapted from FBrf0173155).

Notes on Group

The gene products of blp and CG1409 lack the functionally important HPD motif of the DnaJ domain (FBrf0134627).

Source Material
The HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES Gene Group has been compiled by FlyBase curators using the following publication(s): Li et al., 2016 and Ratheesh et al., 2012 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
Members (43)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
auxilin
auxillin, dAux
black pearl
l(3)01618
l(2)tid, lethal (2) tumorous imaginal discs, lethal(2) tumorous imaginal discs, lethal(2)tumorous imaginal discs, DnaJ
anon-SAGE:Wang-041
Cysteine string protein
cystein string protein, Dcsp, l(3)03988, ab49
DnaJ-like-1
Hsp40, dHDJ1, dHSP40, droj1, DNAJ1
DnaJ-like-60
DnaJ60
Heat shock protein cognate 20
l(3)72Do
lethal (3) 80Fg
l4A, l(3)Lh4A
Receptor mediated endocytosis 8
l(2)45Ba
Tetratricopeptide repeat protein 2
dTPR2, Trp2
External Data
Other resource(s)

[Heat shock protein information resource:Hsp40 ](http://pdslab.biochem.iisc.ernet.in/hspir/hsp40.php)

Synonyms and Secondary IDs
Synonym(s)
HSP40
HEAT SHOCK PROTEIN 40/DNAJ CO-CHAPERONES
DnaJ heat shock proteins
J-proteins
DnaJ domain proteins
Heat shock proteins 40kDa
DnaJ
Secondary FlyBase ID(s)
References (3)