Gene Group: NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE

General Information

Name

NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE

Species

D. melanogaster

Symbol

GLURII

FlyBase ID

FBgg0000570

Date last reviewed

2024-02-29

Number of members

Description

In Drosophila, neuromuscular junction type A and type B glutamate receptors are heterotetramers assembled from either GluRIIA or GluRIIB plus other GluRII subunits. In response to the neurotransmitter, glutamate, they conduct Ca2⁺. (Adapted from FBrf0228432).

Notes on Group

Drosophila NMJ ionotropic glutamate receptors have a pharmacological profile distinct from vertebrate non-NMDA glutamate receptors in that they can be activated by the agonist quisqualate, but do not respond to AMPA or kainate (FBrf0228432).

Source Material

The NON-NMDA IONOTROPIC GLUTAMATE RECEPTORS - GLURII NEUROMUSCULAR JUNCTION-SUBTYPE Gene Group has been compiled using the following publication(s): Han et al., 2015, Ljaschenko et al., 2013, Chorna and Hasan, 2012, Croset et al., 2010, Croset et al., 2010, Benton et al., 2009, and Lee et al., 2009 .

Key Gene Ontology (GO) terms

Molecular Function

glutamate-gated calcium ion channel activity

Biological Process

calcium ion transmembrane transport

Cellular Component

neuromuscular junction

ionotropic glutamate receptor complex

Related Gene Groups

Parent group(s)

CALCIUM CHANNEL SUBUNITS

IONOTROPIC GLUTAMATE RECEPTORS