Gene Group: U7 SM PROTEINS

General Information

Name

U7 SM PROTEINS

Species

D. melanogaster

Symbol

U7-SM

FlyBase ID

FBgg0000647

Date last reviewed

2017-01-31

Number of members

Description

The U7 snRNP is involved in histone mRNA 3' end processing. Sm proteins are common to all small nuclear ribonucleoproteins (snRNPs), assembling in a stepwise manner onto snRNAs, forming a ring-shaped core RNP structure. (Adapted from FBrf0168021 and FBrf0208608).

Notes on Group

U7 snRNP is related to, but biochemically distinct from, spliceosomal snRNPs. The Sm core contains U7-specific Sm-like proteins, Lsm10 and Lsm11, replacing SmD1 and SmD2 in the canonical heptameric Sm protein ring (FBrf0168021, FBrf0208608).

Source Material

The U7 SM PROTEINS Gene Group has been compiled using the following publication(s): Godfrey et al., 2009, Azzouz and Schumperli, 2003, Labourier and Rio, 2001, and Mount and Salz, 2000 .

Key Gene Ontology (GO) terms

Molecular Function

histone pre-mRNA stem-loop binding

Biological Process

mRNA 3'-end processing by stem-loop binding and cleavage

Cellular Component

Lsm-containing SMN-Sm protein complex

Related Gene Groups

Parent group(s)

SM PROTEINS

Protein Complex group(s)

U7 SMALL NUCLEAR RIBONUCLEOPROTEIN PARTICLE