Gene Group: NETRINS

General Information

Name

NETRINS

Species

D. melanogaster

Symbol

NTN

FlyBase ID

FBgg0000714

Date last reviewed

2017-03-23

Number of members

Description

Netrins are secreted axon guidance molecules that guide growing commissural axons towards the midline. They are capable of eliciting either attraction or repulsion of axons by binding to fra or unc-5 receptors. (Adapted from FBrf0191277).

Notes on Group

In Drosophila, the DCC and UNC-5 receptor families are represented by one member only - fra and unc-5, repectively.

Source Material

The NETRINS Gene Group has been compiled using the following publication(s): Organisti et al., 2015, Pert et al., 2015, Orr et al., 2014, Macabenta et al., 2013, Manhire-Heath et al., 2013, Brankatschk and Dickson, 2006, and Guthrie, 1997 .

Key Gene Ontology (GO) terms

Molecular Function

netrin receptor binding

Biological Process

axon guidance

Cellular Component

extracellular region

Related Gene Groups

Members (2)

For all members:

GO ribbon stack