Gene Group: FUCOSYLTRANSFERASES

General Information

Name

FUCOSYLTRANSFERASES

Species

D. melanogaster

Symbol

FUCT

FlyBase ID

FBgg0001293

Date last reviewed

2025-03-06

Number of members

Description

Fucosyltransferases catalyze the transfer of a fucosyl group from GDP-fucose to various acceptor molecules including oligosaccharides, glycoproteins, and glycolipids. Fucosylated carbohydrate structures are involved in a variety of biological processes in eukaryotic organisms including tissue development, angiogenesis, fertilization and cell adhesion. (Adapted from PMID:16973733.)

Notes on Group

FucTA is the only alpha1,3-fucosyltransferase homolog known to possess core alpha1,3-fucosyltransferase activity - FucTB, FucTC and FucTD have restricted expression patterns and do not appear to be catalytically active (FBrf0137268, FBrf0190902), and are therefore excluded from this group.

Source Material

The FUCOSYLTRANSFERASES Gene Group has been compiled using the following publication(s): Yamamoto-Hino et al., 2015, Rendic et al., 2006, and Roos et al., 2002 .

Key Gene Ontology (GO) terms

Molecular Function

fucosyltransferase activity

Biological Process

carbohydrate derivative biosynthetic process

Cellular Component

Related Gene Groups

Parent group(s)

HEXOSYLTRANSFERASES

Members (4)

For all members: