Selected publications for background information: The Drosophila TNF ortholog Eiger: Emerging physiological roles and evolution of the TNF system (FBrf0225608), Drosophila TNF/TNFRs: At the crossroad between metabolism, immunity, and tissue homeostasis (FBrf0257731).
FBrf0256741 shows that in the context of intestinal stem cells wgn can inhibit the JNK cascade. This is in contrast with the role of Tumor Necrosis Factor α signaling in promoting the JNK cascade (FBrf0162270). As this may be independent of the ligand egr, it has not been curated as part of the TNFα-Eiger Signaling Pathway.
| molecular function | biological process | cellular component |
|---|