DEAH-box RNA helicases belong to helicase superfamily 2 (SF2). They are characterized by the presence of nine conserved helicase motifs, including the DEAH sequence in motif II. (Adapted from PMID:21509200.)
Notes on Group
bgcn protein is related to the DExH-box family of RNA-dependent helicases but lacks critical residues for ATPase and helicase functions (FBrf0130002) so is omitted from this group.