Vanins catalyze the hydrolysis of pantetheine to pantothenic acid (vitamin B5), and are thereby involved in recycling Coenzyme A. In humans, they are implicated in inflammation, oxidative stress, cell migration and numerous diseases (Adapted from FBrf0227313 and PMID: 22155241.)
Notes on Group
Biotinidase (Btnd) is part of the same amidohydrolase family as vanins, but it has a different substrate specificity.
