FB2026_03 , released September 17, 2026
Complex: ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEXES
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General Information
Name
ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEXES
Species
D. melanogaster
Symbol
SEC-T
FlyBase ID
FBgg0001921
Date last reviewed
2026-03-26
Number of members
7
Description
Description
The endoplasmic reticulum (ER) Sec translocon complex is required for signal recognition particle (SRP)-independent transport nascent polypeptides of transmembrane and secretory proteins across the ER membrane. The complex is composed of the Sec61 translocon and the Sec62/Sec63 complex. (Adapted from PMID:29263911.)
Notes on Group
Source Material
The ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEXES Gene Group has been compiled using the following publication(s): Attrill, 2023.5.17 and Abrams and Andrew, 2005 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
Cellular Component
endoplasmic reticulum Sec complex
Related Gene Groups
Parent group(s)
GENERAL SECRETORY PATHWAY COMPLEXES
Component group(s)
SEC61 TRANSLOCON - CG8860 VARIANT
SEC61 TRANSLOCON - SEC61γ VARIANT
SEC61 TRANSLOCON - TESTIS-SPECIFIC VARIANT
SEC62/SEC63 COMPLEX
Members (7)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Synonyms and Secondary IDs
Synonym(s)
SEC-T
ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEX SUBUNITS
ENDOPLASMIC RETICULUM SEC TRANSLOCON COMPLEXES
Secondary FlyBase ID(s)
References (3)