The peroxisomal ubiquitin ligase retrotranslocon complex is a transmembrane ubiquitin ligase complex that forms a pore through which the cargo receptor Pex5 is recycled from the peroxisome matrix to the cytosol. Pex5 is ubiquitinated by the E3 ligase activity of the subunits during recycling. Monoubiquitinated Pex5 is extracted from the matrix into the cytosol by the Membrane Extraction Complex ATPase complex. (Adappted from PMID:35768507 and PMID:37743160).