FB2026_02 , released June 18, 2026
Pathway: PROTEIN O-GALACTOSYLATION
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General Information
Name
PROTEIN O-GALACTOSYLATION
Species
D. melanogaster
Symbol
POGAL
FlyBase ID
FBgg0002108
Date last reviewed
2025-03-20
Number of members
2
Description
Description
Protein O-linked galactosylation is a post-translational modification that occurs in the endoplasmic reticulum with the attachment of a galactose via a β-glycosidic bond to the hydroxyl group of hydroxylysine residue. The O-linked galactose can be further extended with glucose. In D. melanogaster, the only known substrate is procollagen. O-linked galactosylation plays a role in the formation of the collagen triple helix, a step required for its secretion. (Adapted from PMID:30822656 and PMID:17516569.)
Notes
Source Material
The PROTEIN O-GALACTOSYLATION Gene Group has been compiled using the following publication(s): Bunt et al., 2011 .
Key Gene Ontology (GO) terms
Biological Process
protein O-linked glycosylation via galactose
Cellular Component
endoplasmic reticulum lumen
Related Gene Groups
Parent group(s)
PROTEIN O-GLYCOSYLATION
GO Causal Activity Model (GO-CAM)
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Note: The Drosophila pathways shown at external resources are computed and may therefore differ from the manually curated and verified pathway shown above.
67b1629100003569
Synonyms and Secondary IDs
Synonym(s)
POGAL
protein O-linked galactose glycan biosynthesis
PROTEIN O-GALACTOSYLATION
Secondary FlyBase ID(s)
References (3)