FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Complex: DBF4-DEPENDENT CDC7 KINASE COMPLEX
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General Information
Name
DBF4-DEPENDENT CDC7 KINASE COMPLEX
Species
D. melanogaster
Symbol
DDK
FlyBase ID
FBgg0002115
Date last reviewed
2025-05-28
Number of members
2
Description
Description
The Dbf4-dependent Cdc7 kinase complex is a serine/threonine-protein kinase that phosphorylates components of the pre-replication complex during DNA replication initiation. (Adapted from FBrf0227432.)
Notes on Group

The DBF4-DEPENDENT CDC7 KINASE COMPLEX was sourced from Complex Portal, curated by EMBL-EBI.

Source Material
The DBF4-DEPENDENT CDC7 KINASE COMPLEX Gene Group has been compiled using the following publication(s): Stephenson et al., 2015 .
Key Gene Ontology (GO) terms
Molecular Function
protein serine/threonine kinase activity
Biological Process
mitotic DNA replication checkpoint signaling
Cellular Component
Dbf4-dependent protein kinase complex
nucleus
Enzymatic activity
Enzyme name (EC)
non-specific serine/threonine protein kinase (2.7.11.1)
tropomyosin kinase (2.7.11.28)
[low-density-lipoprotein receptor] kinase (2.7.11.29)
dephospho-[reductase kinase] kinase (2.7.11.3)
[Goodpasture-antigen-binding protein] kinase (2.7.11.9)
2.7.11.-
Related Gene Groups
Members (2)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
DDK
DBF4-DEPENDENT CDC7 KINASE COMPLEX
Cdc7-Dbf4 complex
Dbf4-dependent kinase complex
Secondary FlyBase ID(s)
References (2)