FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene Group: METCHNIKOWINS
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General Information
Name
METCHNIKOWINS
Species
D. melanogaster
Symbol
METK
FlyBase ID
FBgg0002160
Date last reviewed
2025-12-09
Number of members
3
Description
Description
Metchnikowins are an antimicrobial peptide-encoding gene family induced by the immune deficiency (Imd) signaling pathway. Mtk, the only family member that has been characterized, acts by inhibition of fungal Mitochondrial Complex II (succinate-coenzyme Q reductase). (Adapted from FBrf0236378 and FBrf0263699.)
Notes on Group
Source Material
The METCHNIKOWINS Gene Group has been compiled using the following publication(s): Hanson et al., 2025, Westlake et al., 2024, Tattikota et al., 2020, Hanson et al., 2019, and Imler and Bulet, 2005 .
Key Gene Ontology (GO) terms
Molecular Function
Biological Process
innate immune response
Cellular Component
extracellular space
Related Gene Groups
Parent group(s)
ANTIMICROBIAL PEPTIDES
Members (3)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
METK
METCHNIKOWINS
Secondary FlyBase ID(s)
References (6)