Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\pseudoscute using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\pseudoscute in JBrowse1-11.1 +/- 1.3
1-9.8-12.5
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Locus difficult to map recombinationally since there are closley linked rearrangements (details unspecified) close by the locus.
Mutant phenotypes at psc similar to those caused by mutations at the sc locus. Alleles fall into four classes: weak, middle, strong and extreme. Extreme alleles have a complete absence of bristles on the head and thorax, loss of all but 1-2 bristles from the scutellum and reduction of hairs on the thorax and abdomen.
Superunstable mutations generated in crosses of π2 strain to a wa strain or its derivatives. Each superunstable mutation gives rise to a large family of new super-unstable mutations with a wide range of phenotypic expression. Mutations with the same phenotype often differ in the specificity of their potential for further mutation. Each superunstable mutation is associated with a specific, "paired", reversible mutation. Active transposase encoded by P elements is necessary to maintain superinstability. X transposable element is also implicated in the mutability system.
psc induces bristle reduction.
Source for identity of: pseudoscute psc
The gene symbol "psc" has been changed to "pseudoscute" in order to reduce confusion with the "Psc" ("Posterior sex combs") gene symbol, from which it differed only by case.