FlyBase Gene Report: Dhyd\ftz

General Information

Symbol

Dhyd\ftz

Species

D. hydei

Name

fushi tarazu

Annotation Symbol

Feature Type

protein_coding_gene

FlyBase ID

FBgn0012391

Gene Model Status

Unannotated

Stock Availability

None publicly available

Gene Summary

May play a role in determining neuronal identity, may be directly involved in specifying identity of individual neurons. Required during embryogenesis for the process of body segmentation. Homeotic protein, required in alternating segment primordia, it specifies the correct number of segments (By similarity). (UniProt, P48590)

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All Summaries

Alliance
Auto summary
UniProtKB
Interactive Fly

Summaries

Protein Function (UniProtKB)

(UniProt, P48590)

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Dhyd\ftz

Transgenic constructs containing regulatory region of Dhyd\ftz

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

gene

protein_coding_gene

(FlyBase curators, 2018-)

Stocks and Reagents

Stocks (0)

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Dhyd\ftz has been cloned and sequenced and compared with D.melanogaster ftz. The pattern of Dhyd\ftz expression during early embryonic development has been compared with the pattern of early embryonic D.melanogaster ftz expression.

(Jost et al., 1995)

DNA elements both 3' and 5' to the coding region that are important in proper regulation of expression are the most evolutionarily conserved regions in the vicinity of gene homologs.

(Maier et al., 1993)

The D.melanogaster ftz autoregulatory domain, AE, is a direct target for the ftz homeodomain gene product. Deletion analysis defines multiple elements redundantly involved in enhancer activity. Several of these elements are conserved in the AE homologs of D.virilis and D.hydei and in the developmentally regulated eve and Ubx genes.

(Schier and Gehring, 1993)

Dhyd\ftz has been cloned and sequenced. Comparison with D.melanogaster ftz shows that the overall organisation of the gene is similar in both species. Dhyd\ftz is inverted in the Antp in D.hydei compared to D.melanogaster.

(Maier et al., 1990)

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Dhy-ftz

(Snee et al., 2005)

Dhyd\ftz

ftz

Name Synonyms

fushi tarazu

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 10 )

Sequence Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

CAA56039

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

P48590

Other crossreferences

InterPro - A database of protein families, domains and functional sites

References (6)

Report Sections