Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\MT:DNA using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\MT:DNA in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Temperature-dependent selection in mtDNA transmission is co-operatively regulated by gene products that are encoded by the X, second and third chromosomes.
MT:DNA transmission in the heteroplasmic state is selective and temperature-dependent.
Transmission of two types of MT:DNA are examined at 19oC and 25oC using heteroplasmic lines. Results demonstrate selective transmission of one type of MT:DNA depends on the temperature at which the heteroplasmic lines are maintained.
The temperature-dependency of total electron-transport activity of mitochondria encoded by both MT:DNA and Dmau\MT:DNA does not differ from that of mitochondria encoded by MT:DNA alone. For the selective transmission of mitochondrial DNA in the heteroplasmic state the temperature-dependency of the mitochondrial respiratory function does not appear to play a major role as a selective force.
Temperature-dependent transmission of mitochondrial DNA is investigated in heteroplasmic lines of D.melanogaster established by germ-plasm transplantation. Results suggest that both the nuclear and two types of mitochondrial genomes are involved in the selective transmission of mtDNA. Selection transmission of mtDNA in heteroplasmic lines depends on temperature in all cases of intra- and interspecific combinations.
A very rapid response in the induction of the α-regulatory subunit of the mitochondrial F1-ATPase complex is observed in 37oC heat shocked larvae.
Mitochondrial genes all have the prefix mt:. Data for individual mt genes will be found under the relevant records. This record includes only those data that cannot be conveniently assigned to a particular mt gene, and some general references. The complete D.melanogaster mtDNA sequence is 19,517-bp (Accession number U37541).