Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data
obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the
literature.
The chicken ortholog of lab. Rescue of lab null mutants by the chicken ortholog Hoxb1 demonstrates that the function of Hox genes is phylogenetically conserved.