Updated sequence information for this Drosophila species is no longer provided by FlyBase. Gene model annotations for this species are now updated and maintained at NCBI, using the gnomon automated annotation pipeline. See the NCBI page ‘Eukaryotic genomes annotated at NCBI’.
The FlyBase BLAST tool will continue to support queries against the reference genome of this species, but not queries against annotated transcripts or proteins. For the current release, there is no JBrowse or GBrowse view of the gene model annotations for this species.
The FlyBase archived release FB2017_05 includes the last NCBI annotation update for this species that was imported into FlyBase. That sequence data can be accessed from archived gene reports, via the archived GBrowse tool, and via archived bulk-data downloads.
SR
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The Dpse\SR meiotic drive phenotype is usually associated with three nonoverlapping inversions in the right arm of the X chromosome.
The Dpse\SR X chromosome. when present in males, causes an increased rate of sex chromosome loss but no increase in frequency of diplo-XY sperm.
Study of the frequency of autosomal aneuploid sperm demonstrates high rates of autosomal aneuploidy are not restricted to chromosome 3 but also occur for chromosomes 2, 4 and 5. The overall frequency of autosomal aneuploid sperm is estimated to be approximately 50%. Microscopic studies of meiosis in testes indicated meiotic nondisjunction and meiotic chromosome loss are responsible for the mutant phenotype.
Dpse\SR exhibits both discrete and continuous variation. Discrete variation is caused by X-chromosome meiotic drive. Results conclude there is some evidence for slight distortion of sex-chromosome segregation ratios, the genetic basis of the distortion and its relevance to natural populations remains unknown.
