FlyBase Gene Report: Dmau\OdsH

General Information

Symbol

Dmau\OdsH

Species

D. mauritiana

Name

Odysseus

Annotation Symbol

Feature Type

protein_coding_gene

FlyBase ID

FBgn0026115

Gene Model Status

Unannotated

Stock Availability

None publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Also Known As

OdsH, Ods

Summaries

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 1 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Dmau\OdsH

Transgenic constructs containing regulatory region of Dmau\OdsH

Aberrations (Deficiencies and Duplications) ( 0 )

Inferred from experimentation ( 0 )

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

gene

protein_coding_gene

(FlyBase curators, 2018-)

Stocks and Reagents

Stocks (0)

Genomic Clones (0)

cDNA Clones (0)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

Antibody Information

Laboratory Generated Antibodies

Commercially Available Antibodies

Cell Line Information

Publicly Available Cell Lines

Other Stable Cell Lines

Other Comments

Mapping of the Dmau\OdsH gene shows it can be delineated to a region the size of an average gene, approximately 20kb. While Dmau\OdsH appears to be a discrete element, it requires other nearby genes to be cointrogressed to confer full hybrid sterility: Dmau\OdsH^mau alone is insufficient to cause hybrid sterility in D.simulans.

(Perez and Wu, 1995)

Genetic and molecular analysis suggest the presence of a factor at 16D, named "Odysseus" (Dmau\OdsH), responsible for male sterility of D.mauritiana x D.simulans hybrids. Introgressions of Dsec\OdsH do not cause sterility.

(Perez et al., 1993)

Relationship to Other Genes

Source for database merge of

Source for merge of: Dmau\Ods Dmau\OdsH

(Sun et al., 2004)

Additional comments

A D.melanogaster transcription unit (OdsH) has been isolated which maps to the location of the "Odysseus" locus defined by introgression of D.mauritiana sequences into D.simulans. This transcript has been named OdsH to imply the correspondence in position between the genetic and molecular data without stating their functional equivalence. OdsH is also present in D.mauritiana (Dmau\OdsH) and D.simulans (Dsim\OdsH).

(Ting et al., 1998)

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

Dmau\Ods

Dmau\OdsH

Ods

(Strauss, 1999, Ting et al., 1999, Perez and Wu, 1995, Wu and Palopoli, 1994, Perez et al., 1993)

OdsH

(Lu et al., 2010, Cheng et al., 2008, Poh et al., 2008, Orr, 2005, Sun et al., 2004, Noor and Kliman, 2003)

OdsH^mau

(Chen and Ting, 2005)

Name Synonyms

Ods-site homeobox

(Ting et al., 1998)

Odysseus

(Cheng et al., 2008, Perez et al., 1993)

Secondary FlyBase IDs

FBgn0013831

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 6 )

Sequence Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AF254805

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAF72621

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

Q9NGC1

Other crossreferences

InterPro - A database of protein families, domains and functional sites

References (33)

Report Sections