Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\gav using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\gav in JBrowse1-
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Three alleles have been isolated.
Mutants in gav show an elevated frequency of X chromosome nondisjunction in females. The distribution of crossovers is altered. Crossing over is reduced to approximately 50% of wild type. Mutants are not DNA repair defective as indicated by their lack of sensitivity to methyl methanesulfonate. The mutants are female specific; in hemizygous males there is normal segregation of the X and Y chromosomes.
