Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\p1130 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\p1130 in JBrowsePlease Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
The expression of the 1.6kb p1130 transcript is significantly up-regulated in p1130EP1130 mutant flies compared to controls.
The 1.6kb p1130 transcript does not appear to encode either a functional protein or a mature microRNA, but a 480bp sequence at the 3' end of p1130 is complementary to the 3' UTR of α-Man-I, suggesting that the expression of p1130 can down-regulate the expression of α-Man-I (this is supported by the fact that in p1130EP1130 mutant flies, in which the expression of the p1130 transcript is significantly up-regulated compared to controls, the expression of α-Man-I is decreased compared to controls).
