FlyBase Gene Report: Ecol\TMP

General Information

Symbol

Ecol\TMP

Species

E. coli

Name

TMP tag

Annotation Symbol

Feature Type

engineered_foreign_gene

FlyBase ID

FBgn0267860

Gene Model Status

Not Applicable

Stock Availability

1 publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Foreign Gene Data

Foreign sequence; species == Escherichia coli; gene == 'TMP-tag, an engineered form of the Escherichia coli DHFR (dihydrofolate reductase) gene which forms a covalent bond with trimethoprin derivatives, allowing rapid, irreversible and specific chemical tagging of the protein (see PMID:15782216 and PMID:22873118)'.

(FlyBase Curators, 1992-)

Summaries

Alleles, Insertions, Transgenic Constructs

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Ecol\TMP

Transgenic constructs containing regulatory region of Ecol\TMP

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

lethal, with Scer\GAL4^GH146

Ecol\TMP^{UAS.Tag:Myr(Unk)}

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

engineered_foreign_gene

(FlyBase Curators, 1992-)

Stocks and Reagents

Stocks (1)

Bloomington

58391

w^*; P{UAS-myr-TMP}attP40/CyO; P{UAS-myr-TMP}attP2

Other Comments

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Ecol\TMP

TMP

TMP-tag

(FlyBase Curators, 1992-)

Name Synonyms

TMP tag

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (5)

Report Sections