FlyBase Gene Report: Zzzz\DARPin

General Information

Symbol

Zzzz\DARPin

Species

a. artificial

Name

Designed ankyrin repeat protein

Annotation Symbol

Feature Type

engineered_foreign_gene

FlyBase ID

FBgn0288664

Gene Model Status

Not Applicable

Stock Availability

None publicly available

Gene Summary

Contribute a Gene Snapshot for this gene.

All Summaries

Alliance
Auto summary
Interactive Fly

Foreign Gene Data

Designed ankyrin repeat proteins (DARPins) are artificial peptides that bind a specific protein of interest. DARPins are composed of repeating modules that are based on the ankyrin fold; this sequence consists of a β-turn followed by two antiparallel α-helices and binding specificity is determined by particular residues in the α-helices (reviewed in PMID:25562645, PMID:29374062).

(FlyBase Curators, 1992-)

Summaries

Alleles, Insertions, Transgenic Constructs

Classical and Insertion Alleles ( 0 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of Zzzz\DARPin

Transgenic constructs containing regulatory region of Zzzz\DARPin

Variants

Variant Molecular Consequences

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Phenotype manifest in

Allele

Orthologs

Downloads

Download All DIOPT Orthologs

Model Organism Orthologs (via DIOPT v9.1)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

Drosophila melanogaster (Fruit fly) (0)

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

Interaction Browsers

Summary of Genetic Interactions

Interaction Browsers

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

External Data

Linkouts

Class of Gene

engineered_foreign_gene

(FlyBase Curators, 1992-)

Stocks and Reagents

Stocks (0)

Other Comments

Relationship to Other Genes

Source for database merge of

Additional comments

Nomenclature History

Source for database identify of

Nomenclature comments

Etymology

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

DARΠn

Zzzz\DARPin

Name Synonyms

Designed ankyrin repeat protein

Secondary FlyBase IDs

Datasets (0)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (0)

Result

Result Type

Title

External Crossreferences and Linkouts ( 0 )

References (4)

Report Sections