This report describes general characteristics of the group of diseases classified as atrial septal defect (ASD). ASD is a genetically heterogeneous disorder, with multiple genes and mapped loci. A listing of ASD subtypes, as defined by OMIM, may be found in the table below, with links to more detailed reports for subtypes that have been investigated using fly models.
[updated Dec. 2015 by FlyBase; FBrf0222196]
Atrial septal defect is characterized by a defect in the interatrial septum allowing pulmonary venous return from the left atrium to pass directly to the right atrium. Depending on the size of the defect, this can result in a spectrum of disease; diagnosis may not occur until adulthood. [from Medscape, http://emedicine.medscape.com/article/162914-overview, 2015.12.18]
Congenital heart defect characterized by defects of atrial septation; additional heart abnormalities, such as other defects in septation, defects in chamber growth, or insufficiency of the cardiac valves may be present. [from MIM:611363; 2015.12.18]
Atrial septal defect (ASD) is a genetically heterogeneous disorder, with multiple implicated genes. [from MIM:108800; 2015.12.18]
