FB2026_03 , released September 17, 2026
Human Disease Model Report: advanced sleep phase syndrome
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General Information
Name
advanced sleep phase syndrome
FlyBase ID
FBhh0000265
Disease Ontology Term
Parent Disease
OMIM
Overview

This report describes general characteristics of the group of diseases classified as advanced sleep phase syndrome. Advanced sleep phase syndrome is a genetically heterogeneous disorder, with multiple genes and mapped loci, and is characterized by early sleep onset and early morning offset. A listing of advanced sleep phase syndrome subtypes, as defined by OMIM, may be found in the table below, with links to more detailed reports for subtypes that have been investigated using fly models.

[updated May 2016 by FlyBase; FBrf0222196]

Disease Summary Information
Parent Disease Summary: advanced sleep phase syndrome
OMIM report
Symptoms and phenotype

Advanced sleep phase syndrome is a sleep disorder that involves an altered circadian rhythm resulting in falling asleep in early evening and awaking very early in the morning.

(FlyBase Curators, 2013-)

Advanced sleep phase syndrome is characterized by very early sleep onset and offset (summary by Jones et al., 1999, pubmed:10470086). [From MIM:604348, 2016.05.24]

(OMIM, 2013-)
Genetics
Cellular phenotype and pathology
Molecular information
External links
    Disease synonyms
    familial advanced sleep phase syndrome
    familial advanced sleep-phase syndrome
    FASPS
    Ortholog Information
    Human gene(s) in FlyBase
      Other mammalian ortholog(s) used
        D. melanogaster Gene Information (0)
        Other Genes Used: Viral, Bacterial, Synthetic (0)
          Summary of Physical Interactions (0 groups)
          Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
          Alleles Representing Disease-Implicated Variants
          Genetic Tools, Stocks and Reagents
          Sources of Stocks
          Contact lab of origin for a reagent not available from a public stock center.
          Bloomington Stock Center Disease Page
          Related mammalian, viral, bacterial, or synthetic transgenes
          Allele
          Transgene
          Publicly Available Stocks
          Selected Drosophila transgenes
          Allele
          Transgene
          Publicly Available Stocks
          RNAi constructs available
          Allele
          Transgene
          Publicly Available Stocks
          Selected Drosophila classical alleles
          Allele
          Allele class
          Mutagen
          Publicly Available Stocks
          References (3)