Williams-Beuren syndrome (WBS) or Williams syndrome (WS) results from the hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23 which contains approximately 28 genes; it is inherited as an autosomal dominant. In flies, the gene LIMK1 has been investigated for its contribution to the WBS phenotype (see FBhh0000450).
[updated Nov. 2016 by FlyBase; FBrf0222196]
[WILLIAMS-BEUREN SYNDROME; WBS](https://omim.org/entry/194050)
[WILLIAMS-BEUREN SYNDROME; WBS](https://omim.org/entry/194050)
Williams-Beuren syndrome (WBS) is characterized by mild to moderate intellectual disability, unique personality characteristics, distinctive facial features, and heart and cardiovascular abnormalities. [from Genetics Home Reference, Williams syndrome; 2016.11.28]
Williams syndrome is characterized by a wide spectrum of symptoms and physical features that vary greatly in range and severity, even among affected family members. [from NORD, Williams Syndrome; 2016.11.28]
Williams-Beuren syndrome (WBS) is a contiguous gene deletion syndrome resulting from the hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23 which contains approximately 28 genes; it is inherited as an autosomal dominant. [from MIM:194050; 2016.11.28]
