Inherited retinal diseases are a major cause of severe vision loss worldwide. There are multiple clinical categories of inherited retinal disease, each of which is associated with multiple implicated genes. Retinal diseases modeled in flies are listed in the "Related Diseases" section, below.
References describing biology of this Drosophila system, methods and assays: Lehmann, et al., 2019 (FBrf0240316).
[updated Apr. 2019 by FlyBase; FBrf0222196]
Inherited retinal diseases are estimated to affect over 2 million people worldwide and are a major cause of severe vision loss (Sahel et al., 2015; pubmed:25324231).
Both nuclear and mitochondrial genes are implicated in hereditary retinal disease (Sahel et al., 2015; pubmed:25324231).
