FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Human Disease Model Report: deafness and hearing loss (fly models overview)
Open Close
General Information
Name
deafness and hearing loss (fly models overview)
FlyBase ID
FBhh0001150
Disease Ontology Term
    Parent Disease
    OMIM
    Overview

    This report includes links to reviews and general information on fly models of deafness and hearing loss. Related Drosophila disease models include both nonsyndromic deafness and syndromes that include deafness or hearing loss. In addition, Drosophila orthologs of several genes required for assembly of dynein arms and implicated in ciliary dyskinesia in human have been found to affect auditory perception in flies.

    References describing the biology of the Drosophila auditory system: Li et al., 2018 (FBrf0239051); Albert and Gopfert, 2015 (FBrf0229604); Boekhoff-Falk, 2005 (FBrf0183888).

    [updated Nov. 2019 by FlyBase; FBrf0222196]

    Disease Summary Information
    Disease Summary: deafness and hearing loss (fly models overview)
    OMIM report
    Human gene(s) implicated
    Symptoms and phenotype
    Genetics
    Cellular phenotype and pathology
    Molecular information
    External links
      Disease synonyms
      Ortholog Information
      Human gene(s) in FlyBase
        Other mammalian ortholog(s) used
          D. melanogaster Gene Information (0)
          Other Genes Used: Viral, Bacterial, Synthetic (0)
            Summary of Physical Interactions (0 groups)
            Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
            Alleles Representing Disease-Implicated Variants
            Genetic Tools, Stocks and Reagents
            Sources of Stocks
            Contact lab of origin for a reagent not available from a public stock center.
            Bloomington Stock Center Disease Page
            Related mammalian, viral, bacterial, or synthetic transgenes
            Allele
            Transgene
            Publicly Available Stocks
            Selected Drosophila transgenes
            Allele
            Transgene
            Publicly Available Stocks
            RNAi constructs available
            Allele
            Transgene
            Publicly Available Stocks
            Selected Drosophila classical alleles
            Allele
            Allele class
            Mutagen
            Publicly Available Stocks
            References (14)