FB2026_03 , released September 17, 2026
Human Disease Model Report: muscular dystrophy, limb-girdle, autosomal dominant
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General Information
Name
muscular dystrophy, limb-girdle, autosomal dominant
FlyBase ID
FBhh0001207
Disease Ontology Term
Parent Disease
OMIM
Overview

This report is for muscular dystrophy, limb-girdle (LGMD), autosomal dominant, a form of muscular dystrophy that primarily affects proximal muscles. A list of LGMD autosomal dominant subtypes, as defined by OMIM, can be found by following the links in the "OMIM phenotypic series" section, below. A subset of these can be found in the table below, with links to more detailed reports for subtypes that have been investigated using fly models. See also 'muscular dystrophy, limb-girdle, autosomal recessive' (FBhh0000207).

[updated Mar. 2020 by FlyBase; FBrf0222196]

Disease Summary Information
Parent Disease Summary: muscular dystrophy, limb-girdle, autosomal dominant
OMIM report
Symptoms and phenotype
Genetics
Cellular phenotype and pathology
Molecular information
Disease synonyms
Bethlem myopathy
LGMD
LGMDD
limb-girdle muscular dystrophy
limb girdle muscular dystrophy
Ortholog Information
Human gene(s) in FlyBase
    Other mammalian ortholog(s) used
      D. melanogaster Gene Information (0)
      Other Genes Used: Viral, Bacterial, Synthetic (0)
        Summary of Physical Interactions (0 groups)
        Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
        Alleles Representing Disease-Implicated Variants
        Genetic Tools, Stocks and Reagents
        Sources of Stocks
        Contact lab of origin for a reagent not available from a public stock center.
        Bloomington Stock Center Disease Page
        Related mammalian, viral, bacterial, or synthetic transgenes
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila transgenes
        Allele
        Transgene
        Publicly Available Stocks
        RNAi constructs available
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila classical alleles
        Allele
        Allele class
        Mutagen
        Publicly Available Stocks
        References (4)