FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Cdk12, CycK
FlyBase ID
FBig0000003730
Interaction Network
Interactions Browser links
Cdk12 network
CycK network
Reported Interactions
FBrf0212082-2.coIP.MS
Reference
Bartkowiak et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Cdk12 

dCDK12

bait
CycK 

Cyclin K

prey

2 unique peptides identified

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was nuclear extract of SKc2 cell line; bait produced from endogenous gene; prey produced from endogenous gene.

(Bartkowiak et al., 2010)

No other CDK or cyclin proteins were identified in this coAP-MS experiment.

(Bartkowiak et al., 2010)
FBrf0218395-1362.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
CycK 
unspecified role
CycK 
unspecified role
CycK 
unspecified role
Cdk12 
unspecified role
Cdk12 
unspecified role
Cdk12 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 96.23422

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)