FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Snapin, Dysb
FlyBase ID
FBig0000014239
Interaction Network
Interactions Browser links
Snapin network
Dysb network
Reported Interactions
FBrf0209903-6.Y2H
Reference
Cheli et al., 2010
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Snapin 

Snapin

bait

fused to GAL4 DNA-binding domain

Dysb 

Dysbindin

prey

fused to GAL4 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Cheli et al., 2010)

Two-hybrid system: yeast GAL4-BD/GAL4-AD

(Cheli et al., 2010)
FBrf0218395-5326.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Snapin 
unspecified role
Snapin 
unspecified role
Snapin 
unspecified role
Dysb 
unspecified role
Dysb 
unspecified role
Dysb 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 64.31375

FBrf0227264-1.coIP.MS
Reference
Mullin et al., 2015
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Dysb 

Dsybindin

bait

Venus tag

Snapin 

SNAPIN

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Dysb, Snapin, Muted, Pallidin, Blos1, Blos2, Blos3 and Blos4 constitute the BLOC-1 octameric complex.

(Mullin et al., 2015)

Source was adult heads of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Mullin et al., 2015)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)