FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
eya, Tis11
FlyBase ID
FBig0000095727
Interaction Network
Interactions Browser links
eya network
Tis11 network
Reported Interactions
FBrf0218209-1.PD.WB
Reference
Yeh et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
eya 

eya

bait

biotin tag

eya 
Tis11 

DTIS11

prey

FLAG tag

Tis11 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
eya 
3-prime UTR
sufficient binding region
nt 2511-2730

coordinates relative to eya-RA isoform

Tis11 
TZF RNA-binding domain
necessary binding region
aa 158

F158N mutation abolishes interaction

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Extracts from transfected HEK293T cells expressing Tis11 protein were incubated with biotinylated eya RNA.

(Yeh et al., 2012)

Bait derived from in vitro transcription.

(Yeh et al., 2012)

Prey expressed in transfected HEK293T cells.

(Yeh et al., 2012)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)