FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000096920
Interaction Network
Interactions Browser links
Appl network
APP-BP1 network
Reported Interactions
FBrf0200549-1.PD.A
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Appl 

APPL

bait

GST tag

Appl 

dAPP-BP1

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Appl 
C-terminal region
sufficient binding region
aa 462-524
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

In larval eye disc and brain, overexpression of APP-BP1 increases the level of Appl protein.

In larval eye disc and brain, reduction of APP-BP1 decreases the level of Appl protein.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)