FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Ilp3, ImpL2
FlyBase ID
FBig0000097058
Interaction Network
Interactions Browser links
Ilp3 network
ImpL2 network
Reported Interactions
FBrf0220509-9.coIP.WB
Reference
Okamoto et al., 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Ilp3 

Dilp3

bait

His tag

ImpL2 

Imp-L2

prey

FLAG tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

ImpL2 binds most Ilp proteins tested, except for Ilp7.

(Okamoto et al., 2013)

The Sdr and ImpL2 bind Ilp family proteins with different binding affinities.

(Okamoto et al., 2013)

Sdr and ImpL2 do not bind each other.

(Okamoto et al., 2013)

Source was cell extract of HEK293T cell line; bait produced from transfected construct; prey produced from transfected construct.

(Okamoto et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)