FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000097635
Interaction Network
Interactions Browser links
neur network
Reported Interactions
FBrf0220817-1.Y2H
Reference
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
neur 

Neur

bait

fused to GAL4 DNA-binding domain

neur 

Neur

prey

fused to GAL4 activation domain

neur 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
neur 
NHR1 domain
sufficient binding region
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

Two-hybrid system: yeast GAL4-BD/GAL4-AD

FBrf0220817-4.coIP.WB
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
neur 

Neur

bait

V5 tag

neur 

Neur

prey

FLAG tag

neur 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
neur 
NHR2 domain
mutation decreasing interaction
aa 430

G430E

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of Kc cell line; bait produced from transfected construct; prey produced from transfected construct.

The neur NHR1 domain can interact with the neur NHR2 domain, but neur oligomerization still occurs when both NHR domains are deleted.

External Crossreferences and Linkouts ( 0 )
References (1)