FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Trl, esc
FlyBase ID
FBig0000098217
Interaction Network
Interactions Browser links
Trl network
esc network
Reported Interactions
FBrf0139666-18.coIP.A
Reference
Poux et al., 2001
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage 1embryonic stage 6blastoderm stageembryonic stage 5embryonic stage 3embryonic cycle 6embryonic cycle 8embryonic cycle 5embryonic cycle 7embryonic cycle 4embryonic cycle 3embryonic stage 4embryonic stage 2embryonic cycle 9
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Trl 

gaga

bait
esc 

ESC

prey

LexA DNA binding domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryonic nuclear extract of transgenic fly line; bait produced from endogenous gene; prey produced from tagged transgenic construct.

(Poux et al., 2001)

esc and Trl interact only in early embryos, but not in late embryos. This presumably reflects a transient interaction of esc-containing PRC2 and Trl-containing PRC1 complexes.

(Poux et al., 2001)

Coimmunoprecipitation of tagged prey was determined by pulldown of a radiolabeled LexA DNA probe (that binds specifically to the LexA DNA binding domain).

(Poux et al., 2001)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)