FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Caf1-105, ProtB
FlyBase ID
FBig0000099287
Interaction Network
Interactions Browser links
Caf1-105 network
ProtB network
Reported Interactions
FBrf0222105-10.coIP.WB
Reference
Doyen et al., 2013
Description
physical association
Assay
Collection
Source/Stage
testis / adult stagemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
ProtB 

ProtA/B

bait
Caf1-105 

p75

prey
Caf1-105 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult male testis of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Doyen et al., 2013)

Only the p75 isoform of Caf1-105 coimmunoprecipitates with protamines (Mst35Ba, Mst35Bb) in testis. Caf1 (p55), Caf1-180 and the p105 isoform of Caf1-105 do not interact with protamines.

(Doyen et al., 2013)
FBrf0222105-4.coIP.MS
Reference
Doyen et al., 2013
Description
physical association
Assay
Collection
Source/Stage
testis / adult stagemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Caf1-105 

CAF1-p75/p105

bait
ProtB 

Mst35Bb

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Immunoprecipitated material was washed extensively with 600 mM KCl and 0.1% NP-40.

(Doyen et al., 2013)

Source was adult male testis of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Doyen et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)