FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Caf1-105, Caf1-55
FlyBase ID
FBig0000099346
Interaction Network
Interactions Browser links
Caf1-105 network
Caf1-55 network
Reported Interactions
FBrf0090840-1.CH.coIP.MW
Reference
Tyler et al., 1996
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Caf1-55 

p55

bait
Caf1-105 

p75, p105

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryonic nuclear extract of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Tyler et al., 1996)

Caf1, Caf1-105 and Caf1-180 constitute the CAF-1 complex.

(Tyler et al., 1996)

A partially purified nuclear extract enriched for Caf1 was subjected to immunoprecipitation and copurifying protein bands observed by SDS-PAGE.

(Tyler et al., 1996)
FBrf0222105-2.coIP.MS
Reference
Doyen et al., 2013
Description
physical association
Assay
Collection
Source/Stage
testis / adult stagemale
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Caf1-105 

CAF1-p75/p105

bait
Caf1-55 

CAF1-p55

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Immunoprecipitated material was washed extensively with 600 mM KCl and 0.1% NP-40.

(Doyen et al., 2013)

Source was adult male testis of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Doyen et al., 2013)
FBrf0222105-7.coIP.MS
Reference
Doyen et al., 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Caf1-105 

CAF1-p75/p105

bait
Caf1-55 

CAF1-p55

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Immunoprecipitated material was washed extensively with 600 mM KCl and 0.1% NP-40.

(Doyen et al., 2013)

Source was embryos of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Doyen et al., 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)