FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
tay, rl
FlyBase ID
FBig0000101072
Interaction Network
Interactions Browser links
tay network
rl network
Reported Interactions
FBrf0223725-2.coIP.WB
Reference
Molnar and de Celis, 2013
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
tay 

Tay

bait

FLAG tag

tay 
rl 

ERK[sem]

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
tay 
C-terminal region
sufficient binding region
aa 1456-2486
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos of transgenic fly line; bait produced from tagged transgenic construct; prey produced from tagged transgenic construct.

(Molnar and de Celis, 2013)

The interaction of tay with rl was tested using the rl[Sem] mutant which cannot bind Mkp3 (another tay-binding protein).

(Molnar and de Celis, 2013)
FBrf0223725-4.PD.A
Reference
Molnar and de Celis, 2013
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
rl 

ERK

bait

GST tag

tay 

Tay

prey

[35]S label

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced and labeled by in vitro translation.

(Molnar and de Celis, 2013)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)