FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
KCNQ, Cam
FlyBase ID
FBig0000103672
Interaction Network
Interactions Browser links
KCNQ network
Cam network
Reported Interactions
FBrf0191054-1.Y2H
Reference
Wen et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
KCNQ 

KCNQ

bait
KCNQ 
Cam 

CaM

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
KCNQ 
CaM-binding region
sufficient binding region
aa 300-463

coordinates relative to KCNQ-PE

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Wen et al., 2005)

Two-hybrid system: yeast

(Wen et al., 2005)
FBrf0191054-2.coIP.WB
Reference
Wen et al., 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
KCNQ 

KCNQ

bait
KCNQ 
Cam 

CaM

prey

HA tag

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
KCNQ 
CaM-binding site 1 conserved Arg residue
mutation disrupting interaction
aa 326

R326E, coordinates relative to KCNQ-PE

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was cell extract of tsA201 cell line; bait produced from transfected construct; prey produced from transfected construct.

(Wen et al., 2005)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)