FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000104229
Interaction Network
Interactions Browser links
mir-998 network
Cbl network
Reported Interactions
FBrf0225736-1.miR-mRNA.PCR
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-998

bait
Cbl 

dCbl

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Mutation of mir-998 increases Cbl mRNA levels.

Source was larval eye discs of mutant fly line; bait produced from endogenous gene; prey produced from endogenous gene.

FBrf0225736-2.miR-mRNA.LUC
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note

mir-998

bait
Cbl 

dCbl

prey
Cbl 
Cbl 
Cbl 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Cbl 
CDS
sufficient binding region
Cbl 
mir-998 target site 1
necessary binding region
AGAAGACGCUGGAGAAGACCUGGAAGUUGAUGGACAAGGUGGUCA
Cbl 
mir-998 target site 2
necessary binding region
AGUACCACAUCGCCGGUGCUC
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Luciferase reporter assay.

Source was HeLa cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)