FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
RYBP, Bre1
FlyBase ID
FBig0000104754
Interaction Network
Interactions Browser links
RYBP network
Bre1 network
Reported Interactions
FBrf0226810-15.coIP.WB
Reference
Fereres et al., 2014
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RYBP 

dRYBP

bait
Bre1 

dBRE1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Bre1 coimmunoprecipitates with RYBP but not with Sce or Kdm2.

(Fereres et al., 2014)

RYBP coimmunoprecipitates Sce, Kdm2 and Bre1, but not Psc, Pc, E(z), ph-d or ph-p.

(Fereres et al., 2014)

Source was embryonic nuclear extract of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Fereres et al., 2014)
FBrf0226810-16.coIP.WB
Reference
Fereres et al., 2014
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Bre1 

dBRE1

bait
RYBP 

dRYBP

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Bre1 coimmunoprecipitates RYBP but not Sce or Kdm2.

(Fereres et al., 2014)

Source was embryonic nuclear extract of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Fereres et al., 2014)
FBrf0226810-19.PD.WB
Reference
Fereres et al., 2014
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RYBP 

dRYBP

bait

GST tag

Bre1 

dBRE1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey derived from wild-type embryonic nuclear extract.

(Fereres et al., 2014)
FBrf0226810-3.coIP.MS
Reference
Fereres et al., 2014
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
RYBP 

dRYBP

bait
Bre1 

dBRE1

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryonic nuclear extract of wild-type fly line; bait produced from endogenous gene; prey produced from endogenous gene.

(Fereres et al., 2014)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)