FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000105094
Interaction Network
Interactions Browser links
bin3 network
snRNA:7SKa network
Reported Interactions
FBrf0213172-1.coIP.PCR
Description
physical association
Collection
Cell line used
Participants
Corresponds to
Reported as
Role
Note
bin3 

Bin3

bait

7SK

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was embryos; bait produced from endogenous gene; prey produced from endogenous gene.

FBrf0258314-2.NMR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
bin3 

Bin3

neutral component
bin3 

Bin3

neutral component
bin3 
bin3 

Bin3

neutral component
bin3 

7SK

neutral component

7SK

neutral component

7SK

neutral component
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
bin3 
methyltransferase domain
sufficient binding region
aa 778-1114

coordinates relative to bin3-PA

 
Stem 1 methylation target domain
sufficient binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

The snf-U1 snRNA interaction was curated to the products of all 5 identical or nearly identical U1 snRNA genes.

Interaction in vitro; protein produced as a recombinant fusion protein in bacterial system; RNA cproduced by in vitro transcription.

FBrf0258314-3.EMSA.MW
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
bin3 

Bin3

bait

His tag

bin3 

7SK

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
bin3 
methyltransferase domain
sufficient binding region
aa 778-1114

coordinates relative to bin3-PA

 
Stem 1 methylation target domain
sufficient binding region
unspecified
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced by in vitro transcription.

FBrf0258314-4.coIP.PCR
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
bin3 

Bin3

bait

HA tag

7SK

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult female ovaries; bait produced from tagged transgenic construct; prey produced from endogenous gene.

FBrf0258314-6.ENZ
Reference
Description
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
bin3 

Bin3

enzyme

His tag, H [3] Methionine label

bin3 
bin3 

Bin3

enzyme

His tag, H [3] Methionine label

7SK

enzyme target

7SK

enzyme target
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
External Crossreferences and Linkouts ( 0 )
References (2)