FB2026_02 , released June 18, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
sws, Pka-C3
FlyBase ID
FBig0000105587
Interaction Network
Interactions Browser links
sws network
Pka-C3 network
Reported Interactions
FBrf0206244-1.Y2H
Reference
Bettencourt da Cruz et al., 2008
Description
physical association
Assay
Collection
Source/Stage
organism / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
sws 

SWS

bait

fused to LexA DNA-binding domain

sws 
Pka-C3 

PKA-C3

prey

fused to GAL4 activation domain

Pka-C3 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
sws 
N-terminal region
sufficient binding region
aa 60-241

coordinates relative to sws-PA

Pka-C3 
central region
sufficient binding region
aa 246-482

coordinates relative to Pka-C3-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey from adult cDNA expression library).

(Bettencourt da Cruz et al., 2008)

sws interacts with Pka-C3 but not with Pka-C1 or Pka-C2.

(Bettencourt da Cruz et al., 2008)

Two-hybrid system: yeast LexA-BD/GAL4-AD

(Bettencourt da Cruz et al., 2008)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)