FB2026_03 , released September 17, 2026
Physical Interaction report
Open Close
General Information
Interaction Type
physical association
Interacting Genes
Septin1, Dlip2
FlyBase ID
FBig0000106719
Interaction Network
Interactions Browser links
Septin1 network
Dlip2 network
Reported Interactions
FBrf0144953-19.Y2H
Reference
Shih et al., 2002
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Septin1 

Sep1

bait

fused to LexA DNA-binding domain

Septin1 
Septin1 
Dlip2 

Sip4

prey

fused to B42 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Septin1 
N-terminal region
sufficient binding region
aa 1-325

coordinates relative to Sep1-PA

Septin1 
C-terminal region
sufficient binding region
aa 306-361

coordinates relative to Sep1-PA

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast LexA-BD/B42-AD

(Shih et al., 2002)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey was previously cloned reagent).

(Shih et al., 2002)
FBrf0144953-7.Y2H
Reference
Shih et al., 2002
Description
physical association
Assay
Collection
Source/Stage
organism / embryonic stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Septin1 

Sep1

bait

fused to LexA DNA-binding domain

Dlip2 

Sip4

prey

fused to B42 activation domain

Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Two-hybrid system: yeast LexA-BD/B42-AD

(Shih et al., 2002)

3 Dlip2 clones obtained in the Sep1 screen.

(Shih et al., 2002)

Source was yeast cell line; bait produced as transgenic fusion protein; prey produced as transgenic fusion protein (prey from embryo cDNA expression library).

(Shih et al., 2002)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (1)